A Thiopurine Drug Inhibits West Nile Virus Production in Cell Culture, but Not in Mice

Many viruses within the Flavivirus genus cause significant disease in humans; however, effective antivirals against these viruses are not currently available. We have previously shown that a thiopurine drug, 6-methylmercaptopurine riboside (6MMPr), inhibits replication of distantly related viruses w...

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Bibliographic Details
Main Authors: Lim, Pei-Yin, Keating, Julie A., Hoover, Spencer, Striker, Rob, Bernard, Kristen A.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200352/