Notch Signaling in T-Cell Development and T-ALL

The Notch signaling pathway is an evolutionarily conserved cell signaling system present in most multicellular organisms, as it controls cell fate specification by regulating cell proliferation, differentiation, apoptosis, and survival. Regulation of the Notch signaling pathway can be achieved at mu...

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Bibliographic Details
Main Authors: Li, Xiaoyu, von Boehmer, Harald
Format: Online
Language:English
Published: International Scholarly Research Network 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200084/