TNFAIP3 Maintains Intestinal Barrier Function and Supports Epithelial Cell Tight Junctions

Tight junctions between intestinal epithelial cells mediate the permeability of the intestinal barrier, and loss of intestinal barrier function mediated by TNF signaling is associated with the inflammatory pathophysiology observed in Crohn's disease and celiac disease. Thus, factors that modula...

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Bibliographic Details
Main Authors: Kolodziej, Lauren E., Lodolce, James P., Chang, Jonathan E., Schneider, Jeffrey R., Grimm, Wesley A., Bartulis, Sarah J., Zhu, Xiaorong, Messer, Jeannette S., Murphy, Stephen F., Reddy, Nishith, Turner, Jerrold R., Boone, David L.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198775/