Comparison of D2 dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects

Quetiapine is an established drug for treatment of schizophrenia, bipolar disorder, and major depressive disorder. While initially manufactured as an immediate-release (IR) formulation, an extended-release (XR) formulation has recently been introduced. Pharmacokinetic studies show that quetiapine XR...

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Bibliographic Details
Main Authors: Nord, Magdalena, Nyberg, Svante, Brogren, Jacob, Jucaite, Aurelija, Halldin, Christer, Farde, Lars
Format: Online
Language:English
Published: Cambridge University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198174/