Absence of Wip1 partially rescues Atm deficiency phenotypes in mice
Wildtype p53-Induced Phosphatase 1 (WIP1) is a serine/threonine phosphatase that dephosphorylates proteins in the ataxia telangiectasia mutated (ATM)-initiated DNA damage response pathway. WIP1 may play a homeostatic role in ATM signaling by returning the cell to a normal pre-stress state following...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197977/ |