Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Allogeneic hematopoietic stem cell transplantation (AHSCT) offers the best chance of cure for many patients with congenital and acquired hematologic diseases. Unfortunately, transplantation of alloreactive donor T cells which recognize and damage healthy patient tissues can result in Graft-versus-Ho...

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Bibliographic Details
Main Authors: Davies, Jeff K., Barbon, Christine M., Voskertchian, Annie R., Nadler, Lee M., Guinan, Eva C.
Format: Online
Language:English
Published: MyJove Corporation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197423/