Involvement of Indoleamine 2,3-Dioxygenase in Impairing Tumor-Infiltrating CD8+ T-Cell Functions in Esophageal Squamous Cell Carcinoma

Involvement of Indoleamine 2,3-Dioxygenase in Impairing Tumor-Infiltrating CD8+ T-Cell Functions in Esophageal Squamous Cell Carcinoma

The indoleamine 2,3-dioxygenase-(IDO-) mediated microenvironment plays an important role in tumor immune escape. However, the inhibitory effects of IDO on the CD8+ tumour-infiltrating lymphocytes (CD8+ TILs) in esophageal squamous cell carcinoma (ESCC) have not been clarified yet. Here, we found tha...

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Bibliographic Details
Main Authors: Zhang, Ge, Liu, Wan-Li, Zhang, Lin, Wang, Jun-Ye, Kuang, Miao-Huan, Liu, Peng, Lin, Yue-Hao, Dai, Shu-Qin, Du, Jun
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195535/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195535/

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