APC+/− alters colonic fibroblast proteome in FAP

Here we compared the proteomes of primary fibroblast cultures derived from morphologically normal colonic mucosa of familial adenomatous polyposis (FAP) patients with those obtained from unaffected controls. The expression signature of about 19% of total fibroblast proteins separates FAP mutation ca...

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Bibliographic Details
Main Authors: Patel, Bhavinkumar B., Li, Xin-Ming, Dixon, Maketa P., Blagoi, Elena L., Nicolas, Emmanuelle, Seeholzer, Steven H., Cheng, David, He, Yin A., Coudry, Renata A., Howard, Sharon D., Riddle, Dawn M., Cooper, Harry S., Boman, Bruce M., Conrad, Peggy, Crowell, James A., Bellacosa, Alfonso, Knudson, Alfred, Yeung, Anthony T., Kopelovich, Levy
Format: Online
Language:English
Published: Impact Journals LLC 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195363/