Alzheimer’s and Seizures: Interleukin-18, Indoleamine 2,3-Dioxygenase and Quinolinic Acid
Emergent seizures are common in Alzheimer’s disease (AD), although the mechanisms mediating this are unknown. It is proposed that stress induced interleukin-18 (IL-18), via interferon-gamma (IFNy) and independently, increases indoleamine 2,3-dioxygenase (IDO) and subsequent quinolinic acid (QA) in m...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Libertas Academica
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195251/ |