The Coxiella burnetii Dot/Icm System Creates a Comfortable Home through Lysosomal Renovation
Understanding the molecular pathogenesis of Coxiella burnetii, the causative agent of human Q fever, has historically been hindered by the technical difficulties of genetically manipulating obligate intracellular bacteria. The recent development of culture conditions suitable for axenic propagation...
Main Authors: | Newton, Hayley J., Roy, Craig R. |
---|---|
Format: | Online |
Language: | English |
Published: |
American Society of Microbiology
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195215/ |
Similar Items
-
Effector Protein Translocation by the Coxiella burnetii Dot/Icm Type IV Secretion System Requires Endocytic Maturation of the Pathogen-Occupied Vacuole
by: Newton, Hayley J., et al.
Published: (2013) -
A Screen of Coxiella burnetii Mutants Reveals Important Roles for Dot/Icm Effectors and Host Autophagy in Vacuole Biogenesis
by: Newton, Hayley J., et al.
Published: (2014) -
The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication
by: Carey, Kimberly L., et al.
Published: (2011) -
Dot/Icm Type IVB Secretion System Requirements for Coxiella burnetii Growth in Human Macrophages
by: Beare, Paul A., et al.
Published: (2011) -
Coxiella burnetii Employs the Dot/Icm Type IV Secretion System to Modulate Host NF-κB/RelA Activation
by: Mahapatra, Saugata, et al.
Published: (2016)