Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report

Extramedullary deposits may be the presenting feature of acute myeloid leukemia. An early and accurate diagnosis on cytology will aid in correct patient management. This is especially true for patients with acute megakaryoblastic leukemia (AML M7), where bone marrow aspiration may yield only a dry t...

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Main Authors:	Chitragar, Sanjeev, Agarwal, Shipra, Iyer, Venkateswaran K., Mathur, Sandeep R., Karak, Asis K., Chharchhodawala, Taher, Sharma, Atul, Bakhshi, Sameer
Format:	Online
Language:	English
Published:	Medknow Publications 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193611/

id	pubmed-3193611
recordtype	oai_dc
spelling	pubmed-31936112011-10-21 Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report Chitragar, Sanjeev Agarwal, Shipra Iyer, Venkateswaran K. Mathur, Sandeep R. Karak, Asis K. Chharchhodawala, Taher Sharma, Atul Bakhshi, Sameer Case Report Extramedullary deposits may be the presenting feature of acute myeloid leukemia. An early and accurate diagnosis on cytology will aid in correct patient management. This is especially true for patients with acute megakaryoblastic leukemia (AML M7), where bone marrow aspiration may yield only a dry tap. While cytomorphological features of myeloid sarcoma of other types are well recognized due to its rarity, there are only two case reports discussing the morphological details of megakaryoblastic differentiation on aspiration cytology. We present the case of a 25-year-old patient with extramedullary involvement of lymph node and cerebrospinal fluid by AML M7, describing in detail, the morphological features on aspiration as well as exfoliative cytology. Medknow Publications 2011-09-27 /pmc/articles/PMC3193611/ /pubmed/22022337 http://dx.doi.org/10.4103/1742-6413.85496 Text en Copyright: © 2011 Chitragar, et al.; licensee Cytopathology Foundation Inc. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Chitragar, Sanjeev Agarwal, Shipra Iyer, Venkateswaran K. Mathur, Sandeep R. Karak, Asis K. Chharchhodawala, Taher Sharma, Atul Bakhshi, Sameer
spellingShingle	Chitragar, Sanjeev Agarwal, Shipra Iyer, Venkateswaran K. Mathur, Sandeep R. Karak, Asis K. Chharchhodawala, Taher Sharma, Atul Bakhshi, Sameer Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report
author_facet	Chitragar, Sanjeev Agarwal, Shipra Iyer, Venkateswaran K. Mathur, Sandeep R. Karak, Asis K. Chharchhodawala, Taher Sharma, Atul Bakhshi, Sameer
author_sort	Chitragar, Sanjeev
title	Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report
title_short	Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report
title_full	Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report
title_fullStr	Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report
title_full_unstemmed	Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report
title_sort	cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: a case report
description	Extramedullary deposits may be the presenting feature of acute myeloid leukemia. An early and accurate diagnosis on cytology will aid in correct patient management. This is especially true for patients with acute megakaryoblastic leukemia (AML M7), where bone marrow aspiration may yield only a dry tap. While cytomorphological features of myeloid sarcoma of other types are well recognized due to its rarity, there are only two case reports discussing the morphological details of megakaryoblastic differentiation on aspiration cytology. We present the case of a 25-year-old patient with extramedullary involvement of lymph node and cerebrospinal fluid by AML M7, describing in detail, the morphological features on aspiration as well as exfoliative cytology.
publisher	Medknow Publications
publishDate	2011
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193611/
_version_	1611480865366343680

Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report

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