Identification of lipopolysaccharide-binding peptide regions within HMGB1 and their effects on subclinical endotoxemia in a mouse model

Lipopolysaccharide (LPS) triggers deleterious systemic inflammatory responses when released into the circulation. LPS-binding protein (LBP) in the serum plays an important role in modifying LPS toxicity by facilitating its interaction with LPS signaling receptors, which are expressed on the surface...

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Bibliographic Details
Main Authors: Youn, Ju Ho, Kwak, Man Sup, Wu, Jie, Kim, Eun Sook, Ji, Yeounjung, Min, Hyun Jin, Yoo, Ji-Ho, Choi, Ji Eun, Cho, Hyun-Soo, Shin, Jeon-Soo
Format: Online
Language:English
Published: WILEY-VCH Verlag 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193378/