Immunoglobulin E Receptor Signaling and Asthma*
Elevated IgE levels and increased IgE sensitization to allergens are central features of allergic asthma. IgE binds to the high-affinity Fcϵ receptor I (FcϵRI) on mast cells, basophils, and dendritic cells and mediates the activation of these cells upon antigen-induced cross-linking of IgE-bound Fcϵ...
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| Format: | Online |
| Language: | English |
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American Society for Biochemistry and Molecular Biology
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190874/ |