Human Siglec-5 Inhibitory Receptor and Immunoglobulin A (IgA) Have Separate Binding Sites in Streptococcal β Protein*

Human Siglec-5 Inhibitory Receptor and Immunoglobulin A (IgA) Have Separate Binding Sites in Streptococcal β Protein*

Sialic acid-binding immunoglobulin-like lectins (Siglecs) are receptors believed to be important for regulation of cellular activation and inflammation. Several pathogenic microbes bind specific Siglecs via sialic acid-containing structures at the microbial surface, interactions that may result in m...

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Bibliographic Details
Main Authors: Nordström, Therése, Movert, Elin, Olin, Anders I., Ali, Syed R., Nizet, Victor, Varki, Ajit, Areschoug, Thomas
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190825/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190825/

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