Assessing the pathological relevance of SPINK1 promoter variants

Assessing the pathological relevance of SPINK1 promoter variants

The SPINK1 gene, encoding the human pancreatic secretory trypsin inhibitor, is one of the major genes involved in predisposition to chronic pancreatitis (CP). In this study we have assessed the potential functional impact of 11 SPINK1 promoter variants by means of both luciferase reporter gene assay...

Full description

Bibliographic Details
Main Authors: Boulling, Arnaud, Witt, Heiko, Chandak, Giriraj Ratan, Masson, Emmanuelle, Paliwal, Sumit, Bhaskar, Seema, Reddy, D Nageshwar, Cooper, David N, Chen, Jian-Min, Férec, Claude
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190254/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190254/

Similar Items