Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type
Intermediate filaments (IF) are essential to maintain cellular and nuclear integrity and shape, to manage organelle distribution and motility, to control the trafficking and pH of intracellular vesicles, to prevent stress-induced cell death, and to support the correct distribution of specific protei...
| Main Author: | |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Molecular Diversity Preservation International (MDPI)
2011
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185793/ |
| id |
pubmed-3185793 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-31857932011-10-12 Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type Hertel, Laura Communication Intermediate filaments (IF) are essential to maintain cellular and nuclear integrity and shape, to manage organelle distribution and motility, to control the trafficking and pH of intracellular vesicles, to prevent stress-induced cell death, and to support the correct distribution of specific proteins. Because of this, IF are likely to be targeted by a variety of pathogens, and may act in favor or against infection progress. As many IF functions remain to be identified, however, little is currently known about these interactions. Herpesviruses can infect a wide variety of cell types, and are thus bound to encounter the different types of IF expressed in each tissue. The analysis of these interrelationships can yield precious insights into how IF proteins work, and into how viruses have evolved to exploit these functions. These interactions, either known or potential, will be the focus of this review. Molecular Diversity Preservation International (MDPI) 2011-07-04 /pmc/articles/PMC3185793/ /pubmed/21994768 http://dx.doi.org/10.3390/v3071015 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Hertel, Laura |
| spellingShingle |
Hertel, Laura Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type |
| author_facet |
Hertel, Laura |
| author_sort |
Hertel, Laura |
| title |
Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type |
| title_short |
Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type |
| title_full |
Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type |
| title_fullStr |
Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type |
| title_full_unstemmed |
Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type |
| title_sort |
herpesviruses and intermediate filaments: close encounters with the third type |
| description |
Intermediate filaments (IF) are essential to maintain cellular and nuclear integrity and shape, to manage organelle distribution and motility, to control the trafficking and pH of intracellular vesicles, to prevent stress-induced cell death, and to support the correct distribution of specific proteins. Because of this, IF are likely to be targeted by a variety of pathogens, and may act in favor or against infection progress. As many IF functions remain to be identified, however, little is currently known about these interactions. Herpesviruses can infect a wide variety of cell types, and are thus bound to encounter the different types of IF expressed in each tissue. The analysis of these interrelationships can yield precious insights into how IF proteins work, and into how viruses have evolved to exploit these functions. These interactions, either known or potential, will be the focus of this review. |
| publisher |
Molecular Diversity Preservation International (MDPI) |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185793/ |
| _version_ |
1611479143289978880 |