Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases
Retroviruses are RNA viruses that replicate through a DNA intermediate, in a process catalyzed by the viral reverse transcriptase (RT). Although cellular polymerases and host factors contribute to retroviral mutagenesis, the RT errors play a major role in retroviral mutation. RT mutations that affec...
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| Format: | Online |
| Language: | English |
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Molecular Diversity Preservation International (MDPI)
2009
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185545/ |