Current and Novel Inhibitors of HIV Protease

The design, development and clinical success of HIV protease inhibitors represent one of the most remarkable achievements of molecular medicine. This review describes all nine currently available FDA-approved protease inhibitors, discusses their pharmacokinetic properties, off-target activities, sid...

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Bibliographic Details
Main Authors: Pokorná, Jana, Machala, Ladislav, Řezáčová, Pavlína, Konvalinka, Jan
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185513/