Bradykinin Type-2 Receptor Expression Correlates with Age and Is Subjected to Transcriptional Regulation

Accumulating work in experimental animals suggests that bradykinin (BK) exerts cardioprotective effects via bradykinin type-2 receptors (BK-2Rs). In human end-stage heart failure, BK-2Rs are significantly downregulated by mechanisms that have remained elusive. Heart tissues from idiopathic dilated c...

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Bibliographic Details
Main Authors: Liesmaa, Inka, Shiota, Naotaka, Kokkonen, Jorma O., Kovanen, Petri T., Lindstedt, Ken A.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185256/