Germline BAP1 mutations predispose to malignant mesothelioma

Germline BAP1 mutations predispose to malignant mesothelioma

Because only a small fraction of asbestos-exposed individuals develop malignant mesothelioma1, and because mesothelioma clustering is observed in some families1, we searched for genetic predisposing factors. We discovered germline mutations in BAP1 (BRCA1-associated protein 1) in two families with a...

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Bibliographic Details
Main Authors: Testa, Joseph R., Cheung, Mitchell, Pei, Jianming, Below, Jennifer E., Tan, Yinfei, Sementino, Eleonora, Cox, Nancy J., Dogan, A. Umran, Pass, Harvey I., Trusa, Sandra, Hesdorffer, Mary, Nasu, Masaki, Powers, Amy, Rivera, Zeyana, Comertpay, Sabahattin, Tanji, Mika, Gaudino, Giovanni, Yang, Haining, Carbone, Michele
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184199/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184199/

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