Determinants of Nucleotide-Binding Selectivity of Malic Enzyme

Malic enzymes have high cofactor selectivity. An isoform-specific distribution of residues 314, 346, 347 and 362 implies that they may play key roles in determining the cofactor specificity. Currently, Glu314, Ser346, Lys347 and Lys362 in human c-NADP-ME were changed to the corresponding residues of...

Full description

Bibliographic Details
Main Authors: Hsieh, Ju-Yi, Chen, Meng-Chun, Hung, Hui-Chih
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183043/