Determinants of Nucleotide-Binding Selectivity of Malic Enzyme
Malic enzymes have high cofactor selectivity. An isoform-specific distribution of residues 314, 346, 347 and 362 implies that they may play key roles in determining the cofactor specificity. Currently, Glu314, Ser346, Lys347 and Lys362 in human c-NADP-ME were changed to the corresponding residues of...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183043/ |