The search for allelic variants that cause monogenic disorders or predispose to common, complex polygenic phenotypes
The search for the mutant genes for monogenic disorders has been a spectacular success. This was accomplished because of the mapping and sequencing of the human genome, the determination of the sequence variability, the collection of well-characterized families with mendelian disorders, the developm...
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| Format: | Online |
| Language: | English |
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Les Laboratoires Servier
2001
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181641/ |