Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus

Partetravirus is a recently described group of animal parvoviruses which include the human partetravirus, bovine partetravirus and porcine partetravirus (previously known as human parvovirus 4, bovine hokovirus and porcine hokovirus respectively). In this report, we describe the discovery and genomi...

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Main Authors:	Tse, Herman, Tsoi, Hoi-Wah, Teng, Jade L. L., Chen, Xin-Chun, Liu, Haiying, Zhou, Boping, Zheng, Bo-Jian, Woo, Patrick C. Y., Lau, Susanna K. P., Yuen, Kwok-Yung
Format:	Online
Language:	English
Published:	Public Library of Science 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181347/

id	pubmed-3181347
recordtype	oai_dc
spelling	pubmed-31813472011-10-06 Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus Tse, Herman Tsoi, Hoi-Wah Teng, Jade L. L. Chen, Xin-Chun Liu, Haiying Zhou, Boping Zheng, Bo-Jian Woo, Patrick C. Y. Lau, Susanna K. P. Yuen, Kwok-Yung Research Article Partetravirus is a recently described group of animal parvoviruses which include the human partetravirus, bovine partetravirus and porcine partetravirus (previously known as human parvovirus 4, bovine hokovirus and porcine hokovirus respectively). In this report, we describe the discovery and genomic characterization of partetraviruses in bovine and ovine samples from China. These partetraviruses were detected by PCR in 1.8% of bovine liver samples, 66.7% of ovine liver samples and 71.4% of ovine spleen samples. One of the bovine partetraviruses detected in the present samples is phylogenetically distinct from previously reported bovine partetraviruses and likely represents a novel genotype. The ovine partetravirus is a novel partetravirus and phylogenetically most related to the bovine partetraviruses. The genome organization is conserved amongst these viruses, including the presence of a putative transmembrane protein encoded by an overlapping reading frame in ORF2. Results from the present study provide further support to the classification of partetraviruses as a separate genus in Parvovirinae. Public Library of Science 2011-09-27 /pmc/articles/PMC3181347/ /pubmed/21980506 http://dx.doi.org/10.1371/journal.pone.0025619 Text en Tse et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Tse, Herman Tsoi, Hoi-Wah Teng, Jade L. L. Chen, Xin-Chun Liu, Haiying Zhou, Boping Zheng, Bo-Jian Woo, Patrick C. Y. Lau, Susanna K. P. Yuen, Kwok-Yung
spellingShingle	Tse, Herman Tsoi, Hoi-Wah Teng, Jade L. L. Chen, Xin-Chun Liu, Haiying Zhou, Boping Zheng, Bo-Jian Woo, Patrick C. Y. Lau, Susanna K. P. Yuen, Kwok-Yung Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
author_facet	Tse, Herman Tsoi, Hoi-Wah Teng, Jade L. L. Chen, Xin-Chun Liu, Haiying Zhou, Boping Zheng, Bo-Jian Woo, Patrick C. Y. Lau, Susanna K. P. Yuen, Kwok-Yung
author_sort	Tse, Herman
title	Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
title_short	Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
title_full	Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
title_fullStr	Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
title_full_unstemmed	Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
title_sort	discovery and genomic characterization of a novel ovine partetravirus and a new genotype of bovine partetravirus
description	Partetravirus is a recently described group of animal parvoviruses which include the human partetravirus, bovine partetravirus and porcine partetravirus (previously known as human parvovirus 4, bovine hokovirus and porcine hokovirus respectively). In this report, we describe the discovery and genomic characterization of partetraviruses in bovine and ovine samples from China. These partetraviruses were detected by PCR in 1.8% of bovine liver samples, 66.7% of ovine liver samples and 71.4% of ovine spleen samples. One of the bovine partetraviruses detected in the present samples is phylogenetically distinct from previously reported bovine partetraviruses and likely represents a novel genotype. The ovine partetravirus is a novel partetravirus and phylogenetically most related to the bovine partetraviruses. The genome organization is conserved amongst these viruses, including the presence of a putative transmembrane protein encoded by an overlapping reading frame in ORF2. Results from the present study provide further support to the classification of partetraviruses as a separate genus in Parvovirinae.
publisher	Public Library of Science
publishDate	2011
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181347/
_version_	1611477763970039808

Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus

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