Association of a Polymorphism in the Indoleamine-2,3-Dioxygenase Gene and Interferon-α-Induced Depression in Patients with Chronic Hepatitis C

Association of a Polymorphism in the Indoleamine-2,3-Dioxygenase Gene and Interferon-α-Induced Depression in Patients with Chronic Hepatitis C

Interferon (IFN)-α treatment for infectious diseases and cancer is associated with significant depressive symptoms that can limit therapeutic efficacy. Multiple mechanisms have been implicated in IFN-α-induced depression including immune, neuroendocrine and neurotransmitter pathways. To further expl...

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Bibliographic Details
Main Authors: Smith, Alicia K., Simon, Jason S., Gustafson, Eric L., Noviello, Stephanie, Cubells, Joseph F., Epstein, Michael P., Devlin, David J., Qiu, Ping, Albrecht, Janice K., Brass, Clifford A., Sulkowski, Mark S., McHutchinson, John G., Miller, Andrew H.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179823/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179823/

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