ADAM8 Enhances Osteoclast Precursor Fusion and Osteoclast Formation In Vitro and In Vivo

ADAM8 expression is increased in the interface tissue around a loosened hip prosthesis and in the pannus and synovium of patients with rheumatoid arthritis, but its potential role in these processes is unclear. ADAM8 stimulates osteoclast (OCL) formation, but the effects of overexpression or loss of...

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Bibliographic Details
Main Authors: Ishizuka, Hisako, García-Palacios, Verónica, Lu, Ganwei, Subler, Mark A, Zhang, Heju, Boykin, Christina S, Choi, Sun Jin, Zhao, Liena, Patrene, Kenneth, Galson, Deborah L, Blair, Harry C, Hadi, Tamer M, Windle, Jolene J, Kurihara, Noriyoshi, Roodman, G David
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179311/