Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria

Acetyl salicylic acid (ASA) is metabolized by UDP-glucuronosyltransferase 1A6 (UGT1A6), cytochrome P4502C9 (CYP2C9), and N-acetyl transferase 2 (NAT2). Variations in the activities of these enzymes may modulate adverse ASA-related symptoms such as urticaria. We examined whether polymorphisms in the...

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Bibliographic Details
Main Authors: Palikhe, Nami Shrestha, Kim, Seung-Hyun, Nam, Young Hee, Ye, Young-Min, Park, Hae-Sim
Format: Online
Language:English
Published: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178826/