Subunit Compensation and Plasticity of Synaptic GABAA Receptors Induced by Ethanol in α4 Subunit Knockout Mice
There is considerable evidence that ethanol (EtOH) potentiates γ-aminobutyric acid type A receptor (GABAAR) action, but only GABAARs containing δ subunits appear sensitive to low millimolar EtOH. The α4 and δ subunits co-assemble into GABAARs which are relatively highly expressed at extrasynaptic lo...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Research Foundation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178803/ |