Subunit Compensation and Plasticity of Synaptic GABAA Receptors Induced by Ethanol in α4 Subunit Knockout Mice

There is considerable evidence that ethanol (EtOH) potentiates γ-aminobutyric acid type A receptor (GABAAR) action, but only GABAARs containing δ subunits appear sensitive to low millimolar EtOH. The α4 and δ subunits co-assemble into GABAARs which are relatively highly expressed at extrasynaptic lo...

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Bibliographic Details
Main Authors: Suryanarayanan, Asha, Liang, Jing, Meyer, Edward M., Lindemeyer, A. Kerstin, Chandra, Dev, Homanics, Gregg E., Sieghart, Werner, Olsen, Richard W., Spigelman, Igor
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178803/