The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site

Both cellular environmental factors and chemical modifications critically affect the properties of nucleic acids. However, the structure and stability of DNA containing abasic sites under cell-mimicking molecular crowding conditions remain unclear. Here, we investigated the molecular crowding effect...

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Bibliographic Details
Main Authors: Fujimoto, Takeshi, Nakano, Shu-ichi, Miyoshi, Daisuke, Sugimoto, Naoki
Format: Online
Language:English
Published: SAGE-Hindawi Access to Research 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178115/