Brain-derived neurotrophic factor induces proliferation of human airway smooth muscle cells

Airway diseases such as asthma involve increased airway smooth muscle (ASM) contractility and remodelling via enhanced proliferation. Neurotrophins (NTs) such as brain-derived neurotrophic factor (BDNF), well-known in the nervous system, can regulate Ca2+ signalling, and interact with cytokines in c...

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Bibliographic Details
Main Authors: Aravamudan, Bharathi, Thompson, Michael, Pabelick, Christina, Prakash, Y S
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175295/