The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption

Background. Invasive nontyphoid Salmonella (iNTS) disease is common and severe in adults with human immunodeficiency virus (HIV) infection in Africa. We previously observed that ex vivo macrophages from HIV-infected subjects challenged with Salmonella Typhimurium exhibit dysregulated proinflammatory...

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Main Authors:	Schreiber, Fernanda, Lynn, David J., Houston, Angela, Peters, Joanna, Mwafulirwa, Gershom, Finlay, Brett B., Brinkman, Fiona S. L., Hancock, Robert E. W., Heyderman, Robert S., Dougan, Gordon, Gordon, Melita A.
Format:	Online
Language:	English
Published:	Oxford University Press 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173506/

id	pubmed-3173506
recordtype	oai_dc
spelling	pubmed-31735062011-10-15 The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption Schreiber, Fernanda Lynn, David J. Houston, Angela Peters, Joanna Mwafulirwa, Gershom Finlay, Brett B. Brinkman, Fiona S. L. Hancock, Robert E. W. Heyderman, Robert S. Dougan, Gordon Gordon, Melita A. Major Articles and Brief Reports Background. Invasive nontyphoid Salmonella (iNTS) disease is common and severe in adults with human immunodeficiency virus (HIV) infection in Africa. We previously observed that ex vivo macrophages from HIV-infected subjects challenged with Salmonella Typhimurium exhibit dysregulated proinflammatory cytokine responses. Oxford University Press 2011-10-15 /pmc/articles/PMC3173506/ /pubmed/21917897 http://dx.doi.org/10.1093/infdis/jir512 Text en © The Author 2011. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Schreiber, Fernanda Lynn, David J. Houston, Angela Peters, Joanna Mwafulirwa, Gershom Finlay, Brett B. Brinkman, Fiona S. L. Hancock, Robert E. W. Heyderman, Robert S. Dougan, Gordon Gordon, Melita A.
spellingShingle	Schreiber, Fernanda Lynn, David J. Houston, Angela Peters, Joanna Mwafulirwa, Gershom Finlay, Brett B. Brinkman, Fiona S. L. Hancock, Robert E. W. Heyderman, Robert S. Dougan, Gordon Gordon, Melita A. The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption
author_facet	Schreiber, Fernanda Lynn, David J. Houston, Angela Peters, Joanna Mwafulirwa, Gershom Finlay, Brett B. Brinkman, Fiona S. L. Hancock, Robert E. W. Heyderman, Robert S. Dougan, Gordon Gordon, Melita A.
author_sort	Schreiber, Fernanda
title	The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption
title_short	The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption
title_full	The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption
title_fullStr	The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption
title_full_unstemmed	The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption
title_sort	human transcriptome during nontyphoid salmonella and hiv coinfection reveals attenuated nfκb-mediated inflammation and persistent cell cycle disruption
description	Background. Invasive nontyphoid Salmonella (iNTS) disease is common and severe in adults with human immunodeficiency virus (HIV) infection in Africa. We previously observed that ex vivo macrophages from HIV-infected subjects challenged with Salmonella Typhimurium exhibit dysregulated proinflammatory cytokine responses.
publisher	Oxford University Press
publishDate	2011
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173506/
_version_	1611475733694119936

The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NFκB-Mediated Inflammation and Persistent Cell Cycle Disruption

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