Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem-W domain nucleation

Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem-W domain nucleation

Pathogen proteins targeting the actin cytoskeleton often serve as model systems to understand their more complex eukaryotic analogs. We show that the strong actin filament nucleation activity of Vibrio VopL depends on its three W domains and dimerization through a unique VopL C-terminal domain (VCD)...

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Bibliographic Details
Main Authors: Namgoong, Suk, Boczkowska, Malgorzata, Glista, Michael J., Winkelman, Jonathan D., Rebowski, Grzegorz, Kovar, David R., Dominguez, Roberto
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173040/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173040/

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