Influence of mild and moderate hepatic impairment on axitinib pharmacokinetics
Objective: To evaluate the effects of hepatic impairment on the pharmacokinetics and safety of a single, oral axitinib dose in subjects with mild or moderate hepatic impairment. Methods: In this phase I, open-label, parallel-group study, a total of 24 subjects with either normal hepatic function (n ...
| Main Authors: | , , , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer US
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171651/ |