Autophagosome Precursor Maturation Requires Homotypic Fusion

Autophagy is a catabolic process in which lysosomes degrade intracytoplasmic contents transported in double-membraned autophagosomes. Autophagosomes are formed by the elongation and fusion of phagophores, which can be derived from preautophagosomal structures coming from the plasma membrane and othe...

Full description

Bibliographic Details
Main Authors: Moreau, Kevin, Ravikumar, Brinda, Renna, Maurizio, Puri, Claudia, Rubinsztein, David C.
Format: Online
Language:English
Published: Cell Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171170/