In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation
Coagulase-positive Staphylococcus aureus (S. aureus) is the major causal pathogen of acute endocarditis, a rapidly progressing, destructive infection of the heart valves. Bacterial colonization occurs at sites of endothelial damage, where (together with fibrin and platelets) it initiates the formati...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169740/ |