Medroxyprogesterone Acetate Alters Mycobacterium Bovis BCG-Induced Cytokine Production in Peripheral Blood Mononuclear Cells of Contraceptive Users

Most individuals latently infected with Mycobacterium tuberculosis (M.tb) contain the infection by a balance of effector and regulatory immune responses. This balance can be influenced by steroid hormones such as glucocorticoids. The widely used contraceptive medroxyprogesterone acetate (MPA) posses...

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Bibliographic Details
Main Authors: Kleynhans, Léanie, Du Plessis, Nelita, Black, Gillian F., Loxton, André G., Kidd, Martin, van Helden, Paul D., Walzl, Gerhard, Ronacher, Katharina
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169620/