Donepezil Impairs Memory in Healthy Older Subjects: Behavioural, EEG and Simultaneous EEG/fMRI Biomarkers

Rising life expectancies coupled with an increasing awareness of age-related cognitive decline have led to the unwarranted use of psychopharmaceuticals, including acetylcholinesterase inhibitors (AChEIs), by significant numbers of healthy older individuals. This trend has developed despite very limi...

Full description

Bibliographic Details
Main Authors: Balsters, Joshua H., O'Connell, Redmond G., Martin, Mary P., Galli, Alessandra, Cassidy, Sarah M., Kilcullen, Sophia M., Delmonte, Sonja, Brennan, Sabina, Meaney, Jim F., Fagan, Andrew J., Bokde, Arun L. W., Upton, Neil, Lai, Robert, Laruelle, Marc, Lawlor, Brian, Robertson, Ian H.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169575/