Chlamydia trachomatis Co-opts GBF1 and CERT to Acquire Host Sphingomyelin for Distinct Roles during Intracellular Development

The obligate intracellular pathogen Chlamydia trachomatis replicates within a membrane-bound inclusion that acquires host sphingomyelin (SM), a process that is essential for replication as well as inclusion biogenesis. Previous studies demonstrate that SM is acquired by a Brefeldin A (BFA)-sensitive...

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Bibliographic Details
Main Authors: Elwell, Cherilyn A., Jiang, Shaobo, Kim, Jung Hwa, Lee, Albert, Wittmann, Torsten, Hanada, Kentaro, Melancon, Paul, Engel, Joanne N.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164637/