Molecular Insights into Reprogramming-Initiation Events Mediated by the OSKM Gene Regulatory Network

Molecular Insights into Reprogramming-Initiation Events Mediated by the OSKM Gene Regulatory Network

Somatic cells can be reprogrammed to induced pluripotent stem cells by over-expression of OCT4, SOX2, KLF4 and c-MYC (OSKM). With the aim of unveiling the early mechanisms underlying the induction of pluripotency, we have analyzed transcriptional profiles at 24, 48 and 72 hours post-transduction of...

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Bibliographic Details
Main Authors: Mah, Nancy, Wang, Ying, Liao, Mei-Chih, Prigione, Alessandro, Jozefczuk, Justyna, Lichtner, Björn, Wolfrum, Katharina, Haltmeier, Manuela, Flöttmann, Max, Schaefer, Martin, Hahn, Alexander, Mrowka, Ralf, Klipp, Edda, Andrade-Navarro, Miguel A., Adjaye, James
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164204/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164204/

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