MEF2C Enhances Dopaminergic Neuron Differentiation of Human Embryonic Stem Cells in a Parkinsonian Rat Model

MEF2C Enhances Dopaminergic Neuron Differentiation of Human Embryonic Stem Cells in a Parkinsonian Rat Model

Human embryonic stem cells (hESCs) can potentially differentiate into any cell type, including dopaminergic neurons to treat Parkinson's disease (PD), but hyperproliferation and tumor formation must be avoided. Accordingly, we use myocyte enhancer factor 2C (MEF2C) as a neurogenic and anti-apop...

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Bibliographic Details
Main Authors: Cho, Eun-Gyung, Zaremba, Jeffrey D., McKercher, Scott R., Talantova, Maria, Tu, Shichun, Masliah, Eliezer, Chan, Shing Fai, Nakanishi, Nobuki, Terskikh, Alexey, Lipton, Stuart A.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162026/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162026/

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