Phosphorylation network rewiring by gene duplication

In a comprehensive analysis of phosphoregulatory evolution in yeast, the authors observe that phosphorylation sites tend to be lost after gene duplication and protein network turnover reshuffles kinase–substrate relationships over time.

Bibliographic Details
Main Authors: Freschi, Luca, Courcelles, Mathieu, Thibault, Pierre, Michnick, Stephen W, Landry, Christian R
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159966/