Bacterial Vaginosis and the Natural History of Human Papillomavirus

Objective. To evaluate associations between common vaginal infections and human papillomavirus (HPV). Study Design. Data from up to 15 visits on 756 HIV-infected women and 380 high-risk HIV-uninfected women enrolled in the HIV Epidemiology Research Study (HERS) were evaluated for associations of ba...

Full description

Bibliographic Details
Main Authors:	King, Caroline C., Jamieson, Denise J., Wiener, Jeffrey, Cu-Uvin, Susan, Klein, Robert S., Rompalo, Anne M., Shah, Keerti V., Sobel, Jack D.
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159014/

id	pubmed-3159014
recordtype	oai_dc
spelling	pubmed-31590142011-08-25 Bacterial Vaginosis and the Natural History of Human Papillomavirus King, Caroline C. Jamieson, Denise J. Wiener, Jeffrey Cu-Uvin, Susan Klein, Robert S. Rompalo, Anne M. Shah, Keerti V. Sobel, Jack D. Research Article Objective. To evaluate associations between common vaginal infections and human papillomavirus (HPV). Study Design. Data from up to 15 visits on 756 HIV-infected women and 380 high-risk HIV-uninfected women enrolled in the HIV Epidemiology Research Study (HERS) were evaluated for associations of bacterial vaginosis, trichomoniasis, and vaginal Candida colonization with prevalent HPV, incident HPV, and clearance of HPV in multivariate analysis. Results. Bacterial vaginosis (BV) was associated with increased odds for prevalent (aOR = 1.14, 95% CI: 1.04, 1.26) and incident (aOR = 1.24, 95% CI: 1.04, 1.47) HPV and with delayed clearance of infection (aHR = 0.84, 95% CI: 0.72, 0.97). Whereas BV at the preceding or current visit was associated with incident HPV, in an alternate model for the outcome of incident BV, HPV at the current, but not preceding, visit was associated with incident BV. Conclusion. These findings underscore the importance of prevention and successful treatment of bacterial vaginosis. Hindawi Publishing Corporation 2011 2011-08-16 /pmc/articles/PMC3159014/ /pubmed/21869857 http://dx.doi.org/10.1155/2011/319460 Text en Copyright © 2011 Caroline C. King et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	King, Caroline C. Jamieson, Denise J. Wiener, Jeffrey Cu-Uvin, Susan Klein, Robert S. Rompalo, Anne M. Shah, Keerti V. Sobel, Jack D.
spellingShingle	King, Caroline C. Jamieson, Denise J. Wiener, Jeffrey Cu-Uvin, Susan Klein, Robert S. Rompalo, Anne M. Shah, Keerti V. Sobel, Jack D. Bacterial Vaginosis and the Natural History of Human Papillomavirus
author_facet	King, Caroline C. Jamieson, Denise J. Wiener, Jeffrey Cu-Uvin, Susan Klein, Robert S. Rompalo, Anne M. Shah, Keerti V. Sobel, Jack D.
author_sort	King, Caroline C.
title	Bacterial Vaginosis and the Natural History of Human Papillomavirus
title_short	Bacterial Vaginosis and the Natural History of Human Papillomavirus
title_full	Bacterial Vaginosis and the Natural History of Human Papillomavirus
title_fullStr	Bacterial Vaginosis and the Natural History of Human Papillomavirus
title_full_unstemmed	Bacterial Vaginosis and the Natural History of Human Papillomavirus
title_sort	bacterial vaginosis and the natural history of human papillomavirus
description	Objective. To evaluate associations between common vaginal infections and human papillomavirus (HPV). Study Design. Data from up to 15 visits on 756 HIV-infected women and 380 high-risk HIV-uninfected women enrolled in the HIV Epidemiology Research Study (HERS) were evaluated for associations of bacterial vaginosis, trichomoniasis, and vaginal Candida colonization with prevalent HPV, incident HPV, and clearance of HPV in multivariate analysis. Results. Bacterial vaginosis (BV) was associated with increased odds for prevalent (aOR = 1.14, 95% CI: 1.04, 1.26) and incident (aOR = 1.24, 95% CI: 1.04, 1.47) HPV and with delayed clearance of infection (aHR = 0.84, 95% CI: 0.72, 0.97). Whereas BV at the preceding or current visit was associated with incident HPV, in an alternate model for the outcome of incident BV, HPV at the current, but not preceding, visit was associated with incident BV. Conclusion. These findings underscore the importance of prevention and successful treatment of bacterial vaginosis.
publisher	Hindawi Publishing Corporation
publishDate	2011
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159014/
_version_	1611471550994710528

Bacterial Vaginosis and the Natural History of Human Papillomavirus

Similar Items