Sex-Specific Dynamics of Global Chromatin Changes in Fetal Mouse Germ Cells

Mammalian germ cells undergo global reprogramming of DNA methylation during their development. Global DNA demethylation occurs around the time when the primordial germ cells colonize the embryonic gonads and this coincides with dynamic changes in chromatin composition. Global de novo DNA methylation...

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Bibliographic Details
Main Authors: Abe, Masanobu, Tsai, Shirley Y., Jin, Seung-Gi, Pfeifer, Gerd P., Szabó, Piroska E.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158789/