Identification of a Highly Conserved H1 Subtype-Specific Epitope with Diagnostic Potential in the Hemagglutinin Protein of Influenza A Virus

Subtype specificity of influenza A virus (IAV) is determined by its two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA). For HA, 16 distinct subtypes (H1–H16) exist, while nine exist for NA. The epidemic strains of H1N1 IAV change frequently and cause annual seasonal epidemics as we...

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Bibliographic Details
Main Authors: Zhao, Rongmao, Cui, Shujuan, Guo, Li, Wu, Chao, Gonzalez, Richard, Paranhos-Baccalà, Gláucia, Vernet, Guy, Wang, Jianwei, Hung, Tao
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158760/