Identification and Categorization of Liver Toxicity Markers Induced by a Related Pair of Drugs

Drug-induced liver injury (DILI) is the primary adverse event that results in the withdrawal of drugs from the market and a frequent reason for the failure of drug candidates in the pre-clinical or clinical phases of drug development. This paper presents an approach for identifying potential liver t...

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Bibliographic Details
Main Authors: Chang, Ching-Wei, Beland, Frederick A., Hines, Wade M., Fuscoe, James C., Han, Tao, Chen, James J.
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155372/