Evolution of cagA Oncogene of Helicobacter pylori through Recombination

Helicobacter pylori is a gastric pathogen that infects half the human population and causes gastritis, ulcers, and cancer. The cagA gene product is a major virulence factor associated with gastric cancer. It is injected into epithelial cells, undergoes phosphorylation by host cell kinases, and pert...

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Bibliographic Details
Main Authors: Furuta, Yoshikazu, Yahara, Koji, Hatakeyama, Masanori, Kobayashi, Ichizo
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154945/