Cell-Based Immunotherapy With Mesenchymal Stem Cells Cures Bisphosphonate-Related Osteonecrosis of the Jaw–like Disease in Mice

Cell-Based Immunotherapy With Mesenchymal Stem Cells Cures Bisphosphonate-Related Osteonecrosis of the Jaw–like Disease in Mice

Patients on high-dose bisphosphonate and immunosuppressive therapy have an increased risk of bisphosphonate-related osteonecrosis of the jaw (BRONJ); despite the disease severity, its pathophysiology remains unknown, and appropriate therapy is not established. Here we have developed a mouse model of...

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Bibliographic Details
Main Authors: Kikuiri, Takashi, Kim, Insoo, Yamaza, Takyoshi, Akiyama, Kentaro, Zhang, Qunzhou, Li, Yunsheng, Chen, Chider, Chen, WanJun, Wang, Songlin, Le, Anh D, Shi, Songtao
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154005/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154005/

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