Clostridial Neurotoxins: Mechanism of SNARE Cleavage and Outlook on Potential Substrate Specificity Reengineering
The clostridial neurotoxin family consists of tetanus neurotoxin and seven distinct botulinum neurotoxins which cause the diseases tetanus and botulism. The extreme potency of these toxins primarily relies not only on their ability to specifically enter motoneurons but also on the activity their cat...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Molecular Diversity Preservation International
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153214/ |