Voluntary Wheel Running Reverses Age-Induced Changes in Hippocampal Gene Expression

Normal aging alters expression of numerous genes within the brain. Some of these transcription changes likely contribute to age-associated cognitive decline, reduced neural plasticity, and the higher incidence of neuropathology. Identifying factors that modulate brain aging is crucial for improving...

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Bibliographic Details
Main Authors: Kohman, Rachel A., Rodriguez-Zas, Sandra L., Southey, Bruce R., Kelley, Keith W., Dantzer, Robert, Rhodes, Justin S.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152565/