Integrated Proteomic and Transcriptomic Investigation of the Acetaminophen Toxicity in Liver Microfluidic Biochip

Microfluidic bioartificial organs allow the reproduction of in vivo-like properties such as cell culture in a 3D dynamical micro environment. In this work, we established a method and a protocol for performing a toxicogenomic analysis of HepG2/C3A cultivated in a microfluidic biochip. Transcriptomic...

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Bibliographic Details
Main Authors: Prot, Jean Matthieu, Briffaut, Anne-Sophie, Letourneur, Franck, Chafey, Philippe, Merlier, Franck, Grandvalet, Yves, Legallais, Cécile, Leclerc, Eric
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152546/