Distinct patterns of somatic alterations in a lymphoblastoid and a tumor genome derived from the same individual

Distinct patterns of somatic alterations in a lymphoblastoid and a tumor genome derived from the same individual

Although patterns of somatic alterations have been reported for tumor genomes, little is known on how they compare with alterations present in non-tumor genomes. A comparison of the two would be crucial to better characterize the genetic alterations driving tumorigenesis. We sequenced the genomes of...

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Bibliographic Details
Main Authors: Galante, Pedro A. F., Parmigiani, Raphael B., Zhao, Qi, Caballero, Otávia L., de Souza, Jorge E., Navarro, Fábio C. P., Gerber, Alexandra L., Nicolás, Marisa F., Salim, Anna Christina M., Silva, Ana Paula M., Edsall, Lee, Devalle, Sylvie, Almeida, Luiz G., Ye, Zhen, Kuan, Samantha, Pinheiro, Daniel G., Tojal, Israel, Pedigoni, Renato G., de Sousa, Rodrigo G. M. A., Oliveira, Thiago Y. K., de Paula, Marcelo G., Ohno-Machado, Lucila, Kirkness, Ewen F., Levy, Samuel, da Silva, Wilson A., Vasconcelos, Ana Tereza R., Ren, Bing, Zago, Marco Antonio, Strausberg, Robert L., Simpson, Andrew J. G., de Souza, Sandro J., Camargo, Anamaria A.
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152357/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152357/

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